Mechanisms underlying the regulation of Nedd4-family E3 Ubiquitin ligases

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dc.contributor.advisor Wiesner, Silke (Dr.) Ruetalo Buschinger, Natalia 2018-01-09T10:38:30Z 2018-01-09T10:38:30Z 2020-01-10
dc.identifier.other 1688128433 de_DE
dc.identifier.uri de_DE
dc.description.abstract Nedd4-family enzymes play key roles in the establishment and regulation of both developmental and carcinogenic processes. Hence, profound studies of the catalytic mechanisms and detailed analysis of protein-specific regulation of these enzymes as presented in this thesis, contribute significantly to the understanding of HECT ligases but also may have implications for the development of pharmaceutical inhibitors. en
dc.language.iso en de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-podno de_DE
dc.rights.uri de_DE
dc.rights.uri en
dc.subject.classification Proteine , Magnetische Kernresonanz , Ligasen , Biochemie , Ubiquitinierung , Ubiquitin de_DE
dc.subject.ddc 570 de_DE
dc.subject.other Biochemistry en
dc.subject.other Protein en
dc.subject.other NMR en
dc.subject.other Ubiquitination en
dc.subject.other E3 ligases en
dc.subject.other Nedd4-family en
dc.title Mechanisms underlying the regulation of Nedd4-family E3 Ubiquitin ligases en
dc.type PhDThesis de_DE
dcterms.dateAccepted 2017-12-08
utue.publikation.fachbereich Biochemie de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE


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