The role of the budding yeast RNA-binding proteins Khd1p and Loc1p in mRNA targeting

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dc.contributor.advisor Jansen, Ralf-Peter (Prof. Dr.)
dc.contributor.author Thas Moorthy, Balaji
dc.date.accessioned 2014-10-02T09:07:35Z
dc.date.available 2014-10-02T09:07:35Z
dc.date.issued 2014-10-02
dc.identifier.other 415065763 de_DE
dc.identifier.uri http://hdl.handle.net/10900/56594
dc.identifier.uri http://nbn-resolving.de/urn:nbn:de:bsz:21-dspace-565946 de_DE
dc.description.abstract mRNA localization is the common mechanism used by the cells to attain polarity and cellular asymmetry. In this work, I was focused on two RNA-binding proteins that involve in ASH1 mRNA localization in budding yeast. Khd1p associates with more than 1000 mRNA targets. Majority of them code for cell wall and secretory proteins. My results suggest that it has the potential to associate with endoplasmic reticulum (ER) and it is required for targeting of MID2 mRNA to ER. Loc1p is involved in the formation of nuclear ASH1-mRNP complex. During nuclear export, it is displaced by the She2p-She3p complex. en
dc.language.iso en de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-podok de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=de de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=en en
dc.subject.classification Messenger RNA de_DE
dc.subject.ddc 570 de_DE
dc.title The role of the budding yeast RNA-binding proteins Khd1p and Loc1p in mRNA targeting en
dc.type Dissertation de_DE
dcterms.dateAccepted 2014-09-26
utue.publikation.fachbereich Biochemie de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE

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