Gene Regulation of the Human Trefoil Factor Family (TFF) in Gastrointestinal Cell Lines

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dc.contributor.advisor Gött, Peter de_DE
dc.contributor.author Al-azzeh, Ezzal-din de_DE
dc.date.accessioned 2002-09-25 de_DE
dc.date.accessioned 2014-03-18T10:10:20Z
dc.date.available 2002-09-25 de_DE
dc.date.available 2014-03-18T10:10:20Z
dc.date.issued 2001 de_DE
dc.identifier.other 102363951 de_DE
dc.identifier.uri http://nbn-resolving.de/urn:nbn:de:bsz:21-opus-5921 de_DE
dc.identifier.uri http://hdl.handle.net/10900/48397
dc.description.abstract The trefoil factor family (TFF) is a relatively new family of peptides which bear a three-loop trefoil domain. They appear to play a central role in gastric and luminal mucosal defence, in association with luminal mucins, and they are involved in the healing process following ulceration. The underlying molecular mechanism of TFF peptide action is still unknown, but their physical properties, and the biological activities of these peptides as motogens may prove to be useful as therapeutic agents in ulcerative conditions, including inflammatory bowel disease where present treatment is far from ideal. de_DE
dc.description.abstract The trefoil factor family (TFF) is a relatively new family of peptides which bear a three-loop trefoil domain. They appear to play a central role in gastric and luminal mucosal defence, in association with luminal mucins, and they are involved in the healing process following ulceration. The underlying molecular mechanism of TFF peptide action is still unknown, but their physical properties, and the biological activities of these peptides as motogens may prove to be useful as therapeutic agents in ulcerative conditions, including inflammatory bowel disease where present treatment is far from ideal. en
dc.language.iso de de_DE
dc.publisher Universität Tübingen de_DE
dc.rights ubt-podok de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=de de_DE
dc.rights.uri http://tobias-lib.uni-tuebingen.de/doku/lic_mit_pod.php?la=en en
dc.subject.classification Genregulation de_DE
dc.subject.ddc 540 de_DE
dc.subject.other TFF , Magenkrebs , Immunsystem , Transkriptionsfaktoren de_DE
dc.subject.other Gene regulation , TFF , Gastric Carcinoma , Immunsystem , Transcription factor en
dc.title Gene Regulation of the Human Trefoil Factor Family (TFF) in Gastrointestinal Cell Lines de_DE
dc.title Genregulation der menschlichen Kleeblattfamilie in Zellen des Magen- und Darmtrakts de_DE
dc.type PhDThesis de_DE
dc.date.updated 2009-12-02 de_DE
dcterms.dateAccepted 2001-01-11 de_DE
utue.publikation.fachbereich Sonstige - Biologie de_DE
utue.publikation.fakultaet 7 Mathematisch-Naturwissenschaftliche Fakultät de_DE
dcterms.DCMIType Text de_DE
utue.publikation.typ doctoralThesis de_DE
utue.opus.id 592 de_DE
thesis.grantor 15 Fakultät für Biologie de_DE

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