Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine Scaffold

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Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4-d]pyrrolo[2,3-b]pyridine Scaffold

Author: Forster, Michael; Chaikuad, Apirat; Dimitrov, Teodor; Doering, Eva; Holstein, Julia; Berger, Benedict-Tilman; Gehringer, Matthias; Ghoreschi, Kamran; Mueller, Susanne; Knapp, Stefan; Laufer, Stefan A.
Tübinger Autor(en):
Forster, Michael
Dimitrov, Teodor
Holstein, Julia
Gehringer, Matthias
Ghoreschi, Kamran
Döring, Eva
Laufer, Stefan
Published in: Journal of Medicinal Chemistry (2018), Bd. 61, H. 12, S. 5350-5366
Verlagsangabe: Amer Chemical Soc
Language: English
Full text: http://dx.doi.org/10.1021/acs.jmedchem.8b00571
ISSN: 1520-4804
DDC Classifikation: 540 - Chemistry and allied sciences
Dokumentart: Article
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