Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping

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dc.contributor.author Juchum, Michael
dc.contributor.author Sievers-Engler, Adrian
dc.contributor.author Laufer, Stefan
dc.contributor.author Günther, Marcel Benjamin
dc.contributor.author Döring, Eva
dc.contributor.author Lämmerhofer, Michael
dc.date.accessioned 2017-09-27T11:33:09Z
dc.date.available 2017-09-27T11:33:09Z
dc.date.issued 2017
dc.identifier.issn 1520-4804
dc.identifier.uri http://hdl.handle.net/10900/77972
dc.language.iso en de_DE
dc.publisher Amer Chemical Soc de_DE
dc.relation.uri http://dx.doi.org/10.1021/acs.jmedchem.7b00178 de_DE
dc.rights info:eu-repo/semantics/closedAccess
dc.subject.ddc 540 de_DE
dc.title Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping de_DE
dc.type Artikel de_DE
utue.quellen.id 20170815222223_00475
utue.publikation.seiten 4636-4656 de_DE
utue.personen.roh Juchum, Michael
utue.personen.roh Guenther, Marcel
utue.personen.roh Doering, Eva
utue.personen.roh Sievers-Engler, Adrian
utue.personen.roh Laemmerhofer, Michael
utue.personen.roh Laufer, Stefan
dcterms.isPartOf.ZSTitelID Journal of Medicinal Chemistry de_DE
dcterms.isPartOf.ZS-Issue 11 de_DE
dcterms.isPartOf.ZS-Volume 60 de_DE
utue.fakultaet 07 Mathematisch-Naturwissenschaftliche Fakultät de_DE


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