Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T.

Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

Autor(en):

Mazur, Pawel K.; Herner, Alexander; Mello, Stephano S.; Wirth, Matthias; Hausmann, Simone; Sanchez-Rivera, Francisco J.; Lofgren, Shane M.; Kuschma, Timo; Hahn, Stephan A.; Vangala, Deepak; Trajkovic-Arsic, Marija; Gupta, Aayush; Heid, Irina; Noel, Peter B.; Braren, Rickmer; Erkan, Mert; Kleeff, Joerg; Sipos, Bence; Sayles, Leanne C.; Heikenwalder, Mathias; Hessmann, Elisabeth; Ellenrieder, Volker; Esposito, Irene; Jacks, Tyler; Bradner, James E.; Khatri, Purvesh; Sweet-Cordero, E. Alejandro; Attardi, Laura D.; Schmid, Roland M.; Schneider, Guenter; Sage, Julien; Siveke, Jens T.

Tübinger Autor(en):

Sipos, Bence

Erschienen in:

Nature Medicine (2015), Bd. 21, H. 10, S. 1163-

Verlagsangabe:

Nature Publishing Group

Sprache:

Englisch

Referenz zum Volltext:

http://dx.doi.org/10.1038/nm.3952

ISSN:

1078-8956