Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε

Gama, Fernando H. de Souza; Dutra, Luiz A.; Hawgood, Michael; dos Reis, Caio Vinicius; Serafim, Ricardo A. M.; Ferreira Jr, Marcos A.; Teodoro, Bruno V. M.; Takarada, JessicaEmi; Santiago, Andre S.; Balourdas, Dimitrios-Ilias; Nilsson, Ann-Sofie; Urien, Bruno; Almeida, Vitor M.; Gileadi, Carina; Ramos, Priscila Z.; Salmazo, Anita; Vasconcelos, Stanley N. S.; Cunha, Micael R.; Mueller, Susanne; Knapp, Stefan; Massirer, Katlin B.; Elkins, Jonathan M.; Gileadi, Opher; Mascarello, Alessandra; Lemmens, Bennie B. L. G.; Guimaraes, Cristiano R. W.; Azevedo, Hatylas; Counago, Rafael M.

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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε

Author:

Gama, Fernando H. de Souza; Dutra, Luiz A.; Hawgood, Michael; dos Reis, Caio Vinicius; Serafim, Ricardo A. M.; Ferreira Jr, Marcos A.; Teodoro, Bruno V. M.; Takarada, JessicaEmi; Santiago, Andre S.; Balourdas, Dimitrios-Ilias; Nilsson, Ann-Sofie; Urien, Bruno; Almeida, Vitor M.; Gileadi, Carina; Ramos, Priscila Z.; Salmazo, Anita; Vasconcelos, Stanley N. S.; Cunha, Micael R.; Mueller, Susanne; Knapp, Stefan; Massirer, Katlin B.; Elkins, Jonathan M.; Gileadi, Opher; Mascarello, Alessandra; Lemmens, Bennie B. L. G.; Guimaraes, Cristiano R. W.; Azevedo, Hatylas; Counago, Rafael M.

Tübinger Autor(en):

Serafim, Ricardo A. M.

Published in:

Journal of Medicinal Chemistry (2024), Bd. 67, H. 11, S. 8609-8629

Verlagsangabe:

Washington : Amer Chemical Soc

Language:

English

Full text:

http://dx.doi.org/10.1021/acs.jmedchem.3c02250

ISSN:

0022-2623