Design of a Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

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Design of a Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Author: Wittlinger, Florian; Heppner, David E.; To, Ciric; Guenther, Marcel; Shin, Bo Hee; Rana, Jaimin K.; Schmoker, Anna M.; Beyett, Tyler S.; Berger, Lena M.; Berger, Benedict-Tilman; Bauer, Nicolas; Vasta, James D.; Corona, Cesear R.; Robers, Matthew B.; Knapp, Stefan; Janne, Pasi A.; Eck, Michael J.; Laufer, Stefan A.
Tübinger Autor(en):
Wittlinger, Florian
Laufer, Stefan
Günther, Marcel Benjamin
Published in: Journal of Medicinal Chemistry (2022), Bd. 65, H. 2, S. 1370-1383
Verlagsangabe: Amer Chemical Soc
Language: English
Full text: http://dx.doi.org/10.1021/acs.jmedchem.1c00848
ISSN: 0022-2623
DDC Classifikation: 540 - Chemistry and allied sciences
Dokumentart: Article
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