DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [F-18]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer

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DoE Optimization Empowers the Automated Preparation of Enantiomerically Pure [F-18]Talazoparib and its In Vivo Evaluation as a PARP Radiotracer

Author: Bowden, Gregory D.; Stotz, Sophie; Kinzler, Johannes; Geibel, Christian; Laemmerhofer, Michael; Pichler, Bernd J.; Maurer, Andreas
Tübinger Autor(en):
Stotz, Sophie
Kinzler, Johannes
Geibel, Christian
Maurer, Andreas
Bowden, Gregory David
Lämmerhofer, Michael
Pichler, Bernd
Published in: Journal of Medicinal Chemistry (2021), Bd. 64, H. 21, S. 15690-15701
Verlagsangabe: Washington
Language: English
Full text: http://dx.doi.org/10.1021/acs.jmedchem.1c00903
ISSN: 0022-2623
DDC Classifikation: 540 - Chemistry and allied sciences
Dokumentart: Article
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