Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3 beta Inhibitors with Improved Metabolic Stability

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Discovery and Evaluation of Enantiopure 9H-pyrimido[4,5-b]indoles as Nanomolar GSK-3 beta Inhibitors with Improved Metabolic Stability

Author: Andreev, Stanislav; Pantsar, Tatu; El-Gokha, Ahmed; Ansideri, Francesco; Kudolo, Mark; Anton, Debora Bublitz; Sita, Giulia; Romasco, Jenny; Geibel, Christian; Laemmerhofer, Michael; Goettert, Marcia Ines; Tarozzi, Andrea; Laufer, Stefan A.; Koch, Pierre
Tübinger Autor(en):
Andreev, Stanislav
Pantsar, Tatu
El-Gokha, Ahmed
Ansideri, Francesco
Kudolo, Mark
Geibel, Christian
Lämmerhofer, Michael
Laufer, Stefan
Koch, Pierre
Published in: International Journal of Molecular Sciences (2020), Bd. 21, Article 7823
Verlagsangabe: Mdpi
Language: English
Full text: http://dx.doi.org/10.3390/ijms21217823
ISSN: 1422-0067
DDC Classifikation: 570 - Life sciences; biology
540 - Chemistry and allied sciences
Dokumentart: Artikel
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