Browsing Universitätsbibliographie by Author "Niessner, Heike"

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6-and 8-Prenylnaringenin, Novel Natural Histone Deacetylase Inhibitors Found in Hops, Exert Antitumor Activity on Melanoma Cells

Venturelli, Sascha; Niessner, Heike; Sinnberg, Tobias; Berger, Alexander; Burkard, Markus; Urmann, Corinna; Donaubauer, Kathrin; Boecker, Alexander; Leischner, Christian; Riepl, Herbert; Frank, Jan; Lauer, Ulrich M.; Garbe, Claus; Busch, Christian (2018)
A nexus consisting of beta-catenin and Stat3 attenuates BRAF inhibitor efficacy and mediates acquired resistance to vemurafenib

Sinnberg, Tobias; Makino, Elena; Krueger, Marcel A.; Velic, Ana; Macek, Boris; Rothbauer, Ulrich; Groll, Nicola; Poetz, Oliver; Czemmel, Stefan; Niessner, Heike; Meier, Friedegund; Ikenberg, Kristian; Garbe, Claus; Schittek, Birgit (2016)
Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy

Meraz-Torres, Francisco; Niessner, Heike; Ploeger, Sarah; Riel, Simon; Schoerg, Barbara; Casadei, Nicolas; Kneilling, Manfred; Schaller, Martin; Flatz, Lukas; Macek, Boris; Eigentler, Thomas; Riess, Olaf; Garbe, Claus; Amaral, Teresa; Sinnberg, Tobias (2024)
BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS-mutant melanoma cells: Insights into mode of action and resistance mechanisms

Dinter, Lisa; Karitzky, Paula C.; Schulz, Alexander; Wurm, Alexander A.; Mehnert, Marie-Christin; Sergon, Mildred; Tunger, Antje; Lesche, Mathias; Wehner, Rebekka; Mueller, Anja; Kaeubler, Theresa; Niessner, Heike; Dahl, Andreas; Beissert, Stefan; Schmitz, Marc; Meier, Friedegund; Seliger, Barbara; Westphal, Dana (2024)
BRAF Inhibitors Amplify the Proapoptotic Activity of MEK Inhibitors by Inducing ER Stress in NRAS-Mutant Melanoma

Niessner, Heike; Sinnberg, Tobias; Kosnopfel, Corinna; Smalley, Keiran S. M.; Beck, Daniela; Praetorius, Christian; Mai, Marion; Beissert, Stefan; Kulms, Dagmar; Schaller, Martin; Garbe, Claus; Flaherty, Keith T.; Westphal, Dana; Wanke, Ines; Meier, Friedegund (2017)
Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

Brenner, Ellen; Schoerg, Barbara F.; Ahmetlic, Fatima; Wieder, Thomas; Hilke, Franz Joachim; Simon, Nadine; Schroeder, Christopher; Demidov, German; Riedel, Tanja; Fehrenbacher, Birgit; Schaller, Martin; Forschner, Andrea; Eigentler, Thomas; Niessner, Heike; Sinnberg, Tobias; Boehm, Katharina S.; Hoemberg, Nadine; Braumueller, Heidi; Dauch, Daniel; Zwirner, Stefan; Zender, Lars; Sonanini, Dominik; Geishauser, Albert; Bauer, Juergen; Eichner, Martin; Jarick, Katja J.; Beilhack, Andreas; Biskup, Saskia; Doecker, Dennis; Schadendorf, Dirk; Quintanilla-Martinez, Leticia; Pichler, Bernd J.; Kneilling, Manfred; Mocikat, Ralph; Roecken, Martin (2020)
Case report: Combined CDK4/6 and MEK inhibition in refractory CDKN2A and NRAS mutant melanoma

Forschner, Andrea; Sinnberg, Tobias; Mroz, Gabi; Schroeder, Christopher; Reinert, Christian Philipp; Gatidis, Sergios; Bitzer, Michael; Eigentler, Thomas; Garbe, Claus; Niessner, Heike; Rocken, Martin; Roggia, Cristiana; Armeanu-Ebinger, Sorin; Riess, Olaf; Mattern, Sven; Nann, Dominik; Bonzheim, Irina (2021)
Clinical validation of a prognostic 11-gene expression profiling score in prospectively collected FFPE tissue of patients with AJCC v8 stage II cutaneous melanoma

Amaral, Teresa M. S.; Hoffmann, Marie-Christine; Sinnberg, Tobias; Niessner, Heike; Suelberg, Heiko; Eigentler, Thomas K.; Garbe, Claus (2020)
Combined activity of temozolomide and the mTOR inhibitor temsirolimus in metastatic melanoma involves DKK1

Niessner, Heike; Kosnopfel, Corinna; Sinnberg, Tobias; Beck, Daniela; Krieg, Kathrin; Wanke, Ines; Lasithiotakis, Konstantinos; Bonin, Michael; Garbe, Claus; Meier, Friedegund (2017)
Comparative Analysis of the Antitumor Activity of Cis- and Trans-Resveratrol in Human Cancer Cells with Different p53 Status

Leischner, Christian; Burkard, Markus; Michel, Anja; Berchtold, Susanne; Niessner, Heike; Marongiu, Luigi; Busch, Christian; Frank, Jan; Lauer, Ulrich M.; Venturelli, Sascha (2021)
Cytotoxicity of new duplex drugs linking 3 '-C-ethynylcytidine and 5-fluor-2 '-deoxyuridine against human melanoma cells

Schott, Sarah; Niessner, Heike; Sinnberg, Tobias; Venturelli, Sascha; Berger, Alexander; Ikenberg, Kristian; Villanueva, Jessie; Meier, Friedegund; Garbe, Claus; Busch, Christian (2012)
Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases

Chatziioannou, Eftychia; Rossner, Jana; Aung, Thazin New; Rimm, David L.; Niessner, Heike; Keim, Ulrike; Serna-Higuita, Lina Maria; Bonzheim, Irina; Cuellar, Luis Kuhn; Westphal, Dana; Steininger, Julian; Meier, Friedegund; Pop, Oltin Tiberiu; Forchhammer, Stephan; Flatz, Lukas; Eigentler, Thomas; Garbe, Claus; Roecken, Martin; Amaral, Teresa; Sinnberga, Tobias (2023)
Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients

Hilke, Franz J.; Sinnberg, Tobias; Gschwind, Axel; Niessner, Heike; Demidov, German; Amaral, Teresa; Ossowski, Stephan; Bonzheim, Irina; Roecken, Martin; Riess, Olaf; Garbe, Claus; Schroeder, Christopher; Forschner, Andrea (2020)
Disulfiram as a Therapeutic Agent for Metastatic Malignant Melanoma-Old Myth or New Logos?

Meraz-Torres, Francisco; Ploeger, Sarah; Garbe, Claus; Niessner, Heike; Sinnberg, Tobias (2020)
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy

Bochem, Jonas; Zelba, Henning; Spreuer, Janine; Amaral, Teresa; Gaissler, Andrea; Pop, Oltin T.; Thiel, Karolin; Yurttas, Can; Soffel, Daniel; Forchhammer, Stephan; Sinnberg, Tobias; Niessner, Heike; Meier, Friedegund; Terheyden, Patrick; Koenigsrainer, Alfred; Garbe, Claus; Flatz, Lukas; Pawelec, Graham; Eigentler, Thomas K.; Loeffler, Markus W.; Weide, Benjamin; Wistuba-Hamprecht, Kilian (2022)
Embryonic bone morphogenetic protein and nodal induce invasion in melanocytes and melanoma cells

Sinnberg, Tobias; Niessner, Heike; Levesque, Mitchell P.; Dettweiler, Christoph; Garbe, Claus; Busch, Christian (2018)
Epigenetic impacts of ascorbate on human metastatic melanoma cells

Venturelli, Sascha; Sinnberg, Tobias; Berger, Alexander; Noor, Seema; Levesque, Mitchell P.; Böcker-Felbek, Alexander Dietmar; Niessner, Heike; Lauer, Ulrich Manfred; Bitzer, Michael; Garbe, Claus; Busch, Christian (2014)
Ex Vivo Evaluation of the Sepsis Triple Therapy High-Dose Vitamin C in Combination with Vitamin B1 and Hydrocortisone in a Human Peripheral Blood Mononuclear Cells (PBMCs) Model

Lauer, Annie; Burkard, Markus; Niessner, Heike; Leischner, Christian; Renner, Olga; Vollbracht, Claudia; Michels, Holger; Busch, Christian; Sinnberg, Tobias; Venturelli, Sascha (2021)
Exploring the In Vitro and In Vivo Therapeutic Potential of BRAF and MEK Inhibitor Combination in NRAS-Mutated Melanoma

Niessner, Heike; Huesch, Anna; Kosnopfel, Corinna; Meinhardt, Matthias; Westphal, Dana; Meier, Friedegund; Schilling, Bastian; Sinnberg, Tobias (2023)
Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors

Gassenmaier, Maximilian; Rentschler, Maximilian; Fehrenbacher, Birgit; Eigentler, Thomas K.; Ikenberg, Kristian; Kosnopfel, Corinna; Sinnberg, Tobias; Niessner, Heike; Boesmueller, Hans; Wagner, Nikolaus B.; Schaller, Martin; Garbe, Claus; Roecken, Martin (2020)

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