During vertebrate evolution, the development of an active, predatory lifestyle and an increased body size coincided with the appearance of many morphological innovations. Among these vertebrate-specific phenotypic features, ...
Diabetes is a global disease with a strongly increasing prevalence and incidence. In Germany, about 9 million people are living with diabetes, most of them with type 2. Type 2 diabetes impairs vascularization, nerve signal ...
Nucleosome, the basic structure of chromatin and normal product of cell apoptosis, plays a pivotal role in both the induction and pathogenesis of systemic lupus erythematosus (SLE). Nucleosomes are found to circulate at ...
Ischemic preconditioning (IP) represents a powerful experimental strategy to identify novel molecular targets to attenuate hepatic injury during ischemia. As a result, murine studies of hepatic IP have become an important ...
The hippocampus (HPC) and prefrontal cortex (PFC), two critical brain regions which support several basic brain functions, are essential for our daily life. For instance, as one of the most important brain functions, the ...
Retinitis Pigmentosa (RP) is an inherited eye disease which causes progressive
photoreceptor degeneration and consequently blindness in humans. So far, there has been no found cure or reliable treatment for RP. The retinal ...