P. falciparum, T. gondii and T. brucei parasites cause infectious diseases that affect more than 300-400 million people world-wide and, thus, represent a major health problem. The rapid spreading of drug resistant parasite ...
BK channels respond to elevations in intracellular calcium and membrane depolarization, and inhibit the excitability of smooth muscles. This study addressed the role of BK channels in arteries and urinary bladder by using ...
The caseinolytic protease Clp, highly conserved in eubacteria and eukaryotes, degrades misfolded proteins as well as short-lived regulatory factors by targeted proteolysis. The Clp degradation machinery consists of two ...
In eukaryotic cells, the nucleus is enclosed by the two continuous membranes of the
nuclear envelope establishing a physical barrier that spatially separates the
nucleoplasm from the cytoplasm. To accommodate bidirectional ...
Phänotypische oder entwicklungsbedingte Plastizität ist der Prozess, durch den identische Genotypen unterschiedliche Phänotypen in Reaktion auf Umweltreize hervorrufen können. Phänotypische Plastizität kann auch als ...
Light guides marine invertebrate larvae to their settlement places. A light guided behavior is phototaxis, which is mediated by opsins. Among the opsins, the Go‑opsins are ancient, but poorly characterized, because they ...
The interleukin-2 receptor common gamma chain gene (IL2RG) encodes for the common gamma chain (yc), which is a part of multiple interleukin receptors such as IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21 receptor. T cell ...
Cell division and cell expansion are fundamentally important processes of plant development. Although, many proteins have been functionally characterized and implicated in those processes, there is still a lot to investigate. ...
Epilepsie ist eine der häufigsten neurologischen Erkrankungen weltweit. Epilepsie kann
viele unterschiedliche Ätiologien haben. Monogetische Veränderungen machen einen
kleinen Bruchteil hieran aus. In dieser Arbeit wurden ...